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Effect of fluorouracil, leucovorin, and oxaliplatin with or without onartuzumab in HER2-negative, MET-positive gastroesophageal adenocarcinoma: the METGastric randomized clinical trial

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Wang et al., 2023) (Figs

While oral capsules offer a practical option for gut and tissue support, they are not a substitute for medical treatment

While human data is more limited, case reports from 2025-2026 suggest similar benefits in clinical practice, with women reporting improved mobility and reduced pain during menstruation

Physicians must also consider FDA law and malpractice insurance coverage